15-03-2013 \u2013 Lancet. 1992 Apr 25;339(8800):1003-7<\/div>\n

Olsen SF, S\u00f8rensen JD, Secher NJ, Hedegaard M, Henriksen TB, Hansen HS, Grant A.<\/p>\n

Abstract<\/strong><\/p>\n

The high birthweights and long duration of pregnancy in the Faroe Islands led us to suggest that a high intake of marine-fat-derived n-3 fatty acids might prolong pregnancy by shifting the balance of production of prostaglandins involved in parturition. We have compared the effects on pregnancy duration, birthweight, and birth length of a fish-oil supplement, a control olive-oil supplement, and no supplementation. 533 healthy Danish women in week 30 of pregnancy were randomly assigned in a ratio of 2\/1\/1 to fish oil (four 1 g Pikasol capsules [containing 2.7 g n-3 fatty acids] per day), olive oil (four 1 g capsules per day), or no supplement. The three groups differed in mean length of gestation (p = 0.006), which was highest in the fish-oil group and lowest in the olive-oil group; the result was similar when the analysis was restricted to women with an estimate of gestation length based on early ultrasound findings (443 women). Pregnancies in the fish-oil group were on average 4.0 (95% confidence interval 1.5-6.4) days longer than those in the olive-oil group; the difference in birthweight was 107 (1-214) g. The effect of supplementation on length of gestation was influenced by intake of fish and of fish oil: the difference between fish-oil and other groups was increased by a low fish intake at baseline. Fish-oil supplementation in the third trimester seems to prolong pregnancy without detrimental effects on the growth of the fetus or on the course of labour.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

15-03-2013 \u2013 Lancet. 1992 Apr 25;339(8800):1003-7 Olsen SF, S\u00f8rensen JD, Secher NJ, Hedegaard M, Henriksen TB, Hansen HS, Grant A. Abstract The high birthweights and long [\u2026]<\/span><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[40],"tags":[],"class_list":["post-361","post","type-post","status-publish","format-standard","hentry","category-bibliografia-metra"],"_links":{"self":[{"href":"https:\/\/www.pharmarte.com\/en\/wp-json\/wp\/v2\/posts\/361","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.pharmarte.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.pharmarte.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.pharmarte.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.pharmarte.com\/en\/wp-json\/wp\/v2\/comments?post=361"}],"version-history":[{"count":1,"href":"https:\/\/www.pharmarte.com\/en\/wp-json\/wp\/v2\/posts\/361\/revisions"}],"predecessor-version":[{"id":362,"href":"https:\/\/www.pharmarte.com\/en\/wp-json\/wp\/v2\/posts\/361\/revisions\/362"}],"wp:attachment":[{"href":"https:\/\/www.pharmarte.com\/en\/wp-json\/wp\/v2\/media?parent=361"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.pharmarte.com\/en\/wp-json\/wp\/v2\/categories?post=361"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.pharmarte.com\/en\/wp-json\/wp\/v2\/tags?post=361"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}