Bibliografia Mthfr Prevent PLUS

4 agosto 2017

Randomized multicenter investigation of folate plus vitamin B12 supplementation inschizophrenia.

Roffman JL1, Lamberti JS, Achtyes E, Macklin EA, Galendez GC, Raeke LH, Silverstein NJ, Smoller JW, Hill M, Goff DC. Abstract IMPORTANCE: More effective treatments are needed for negative symptoms of schizophrenia, which are typically chronic, […]
4 agosto 2017

Prevention of congenital malformations and other adverse pregnancy outcomes with4.0 mg of folic acid: community-based randomized clinical trial in Italy and the Netherlands.

Bortolus R1, Blom F, Filippini F, van Poppel MN, Leoncini E, de Smit DJ, Benetollo PP, Cornel MC, de Walle HE, Mastroiacovo P;Italian and Dutch folic acid trial study groups. BACKGROUND: In 2010 a Cochrane review confirmed […]
4 agosto 2017

L-methylfolate as adjunctive therapy for SSRI-resistant major depression: results of two randomized, double-blind, parallel-sequential trials.

Papakostas GI1, Shelton RC, Zajecka JM, Etemad B, Rickels K, Clain A, Baer L, Dalton ED, Sacco GR, Schoenfeld D, Pencina M,Meisner A, Bottiglieri T, Nelson E, Mischoulon D, Alpert JE, Barbee JG, Zisook S, Fava M. Abstract OBJECTIVE: The authors conducted two multicenter […]
4 agosto 2017

Is 5-methyltetrahydrofolate an alternative to folic acid for the prevention of neural tube defects?

Obeid R1, Holzgreve W, Pietrzik K. Abstract Women have higher requirements for folate during pregnancy. An optimal folate status must be achieved before conception and in the first […]
4 agosto 2017

Folic acid and L-5-methyltetrahydrofolate: comparison of clinical pharmacokinetics and pharmacodynamics.

Pietrzik K1, Bailey L, Shane B. Abstract There is a large body of evidence to suggest that improving periconceptional folate status reduces the risk of neonatal neural tube defects. […]
4 agosto 2017

Folate, folic acid and 5-methyltetrahydrofolate are not the same thing.

Scaglione F1, Panzavolta G. Author information Abstract Folate, an essential micronutrient, is a critical cofactor in one-carbon metabolism. Mammals cannot synthesize folate and depend on supplementation to maintain normal […]
4 agosto 2017

Effects of folic acid supplementation on overall and site-specific cancer incidenceduring the randomised trials: meta-analyses of data on 50,000 individuals.

Vollset SE1 et al. Abstract BACKGROUND: Some countries fortify flour with folic acid to prevent neural tube defects but others do not, partly because of concerns about possible cancer risks. We aimed […]